Aciphex Lawsuit Lawyer
Please Note: Our law firm no longer accepts Aciphex cases.Aciphex, a popular drug for heartburn, has been linked to an increased risk of kidney inflammation (nephritis), renal disease, bone fractures, and other serious side effects. The FDA has issued several warnings about risks concerning Aciphex and other proton pump inhibitor (PPI) drugs.
Related: Proton Pump Inhibitor (PPI) Lawsuit
The Journal of the American Society of Nephrology published a study in April 2016 that linked long-term use of antacid medications such as Aciphex with a 96% increased risk of kidney failure and a 26% increased risk of chronic kidney disease.
What is Aciphex?
Aciphex (rabeprazole) is a type of drug known as a Proton Pump Inhibitor (PPI). Aciphex is made by Eisai Co. and distributed by Janssen Pharmaceuticals. Inc.
Aciphex is used in the treatment of maladies caused when the stomach produces too much acid. Most people take Aciphex for heartburn (so-called), or gastroesophageal reflux disease. GERD occurs when stomach acid overflows into the esophagus. Aciphex reduces stomach acid, which helps the body heal damaged esophageal tissue, or ulcers in the stomach.
Related: Protonix Lawsuit
Aciphex Kidney Damage
In December 2014, the FDA updated Aciphex’ label to strengthen warnings about acute interstitial nephritis. This sudden swelling and inflammation in the kidneys results from an allergic reaction to Aciphex. Without treatment, it can lead to kidney failure.
In January 2016, Johns Hopkins’ researchers published a study linking PPIs with higher rates of Chronic Kidney Disease (CKD). The study found that people who use PPIs once or twice daily face a 20-50% increased risk of kidney disease. CKD damages the kidneys by reducing their ability to clean the blood, which can lead to kidney failure.
In April 2015, PPIs were linked to acute kidney injury and nephritis. A study was published by the medical journal CMAJ Open. Researchers analyzed data on 290,000 Canadians who began taking PPIs between 2002 and 2011. They found a 2.5-fold increased risk of acute kidney injury, as well as a tripled increased risk of nephritis.
Safety Warnings for Bone Fractures
Aciphex has also been linked with bone fractures. In April 2012, U.K. health regulators issued a warning about bone fractures linked with heartburn drugs. The agency warned that the increased risk of bone fractures was highest for people who had taken PPIs for more than a calendar year. Furthermore, they warned that elderly people appeared to have the highest risk of bone fractures.
FDA Bone Fracture Risk Warning
In May 2010, the U.S. FDA warned that PPIs could increase bone fracture risks. The warning came after a review of several studies which had linked long-term PPI use to an increased risk of bone fractures. Again, the highest risk was for those who used PPIs for more than a year.
Acute Interstitial Nephritis
Chronic Kidney Disease (CKD)
Bone fractures (especially of the wrist, spine, and hip)
Tetany (muscle spasm)
Arrhythmia, heart problems
Aciphex Lawsuit Evaluation
Matthews & Associates is evaluating Aciphex linked injury cases in all 50 states and Puerto Rico. If you or someone you know was diagnosed with kidney problems following use of Aciphex or other PPIs, contact our law offices for a free legal consultation. Email us through this form or call 888-520-5202.